SUBLINGUAL AND ORAL FILMS -A PROMISING FORMULATION FOR ANTIEMETIC DRUGS

Abstract

Orally fast dissolving sublingual film gives better patients compliance over tablet formulation which is considered as most versatile oral formulations. It gives quick onset of action, easy administration. This formulations are suitable for anti-emetic drugs. It is placed in the oral cavity and dissolved in the saliva and gives quick action and the biggest advantage of this formulation is it can be administered without water. These oral films are formulated by using polymers, plasticizers, flavours, colours and sweeteners as excipients along with drug. There are many preparation methods for the oral films but most prominent used method is solvent casting. These films can be evaluate for thickness variation, tensile strength, content uniformity, in vitro drug release and stability studies. There are wide spectrum of application of fast dissolving sublingual films in pharmaceutical formulations.